Table 5.
The stability of VD3 liposomes in different time and temperature. Polydispersity index (PDI).
| 4 °C | VD3 Solution | VD3 Liposomes | ||
| Day | Content (μg/mL) | Content (μg/mL) | EE% | Size (nm)/PDI |
| 1 | 98.74 ± 1.69 | 96.56 ± 2.35 | 87.24 ± 1.07 | 107.7/0.11 |
| 3 | 93.56 ± 1.19 | 96.37 ± 1.03 | 87.11 ± 1.40 | 115.4/0.18 |
| 5 | 87.34 ± 1.01 | 95.74 ± 0.63 | 86.88 ± 1.65 | 126.2/0.15 |
| 7 | 82.11 ± 1.09 | 95.15 ± 1.75 | 86.58 ± 1.39 | 133.0/0.25 |
| 9 | 78.40 ± 1.66 | 94.89 ± 1.75 | 86.41 ± 1.37 | 150.9/0.33 |
| 25 °C | VD3 Solution | VD3 Liposomes | ||
| Day | Content (μg/mL) | Content (μg/mL) | EE% | Size (nm)/PDI |
| 1 | 97.27 ± 1.61 | 95.24 ± 0.34 | 86.69 ± 1.58 | 109.6/0.15 |
| 3 | 92.08 ± 2.29 | 95.13 ± 1.74 | 86.58 ± 0.72 | 104.7/0.17 |
| 5 | 85.46 ± 1.98 | 94.88 ± 0.61 | 85.17 ± 0.40 | 113.6/0.17 |
| 7 | 78.31 ± 2.53 | 94.60 ± 0.86 | 85.24 ± 1.33 | 120.9/0.21 |
| 9 | 73.36 ± 1.31 | 93.98 ± 1.45 | 85.09 ± 0.32 | 135.9/0.25 |
| 4 0 °C | VD3 Solution | VD3 Liposomes | ||
| Day | Content (μg/mL) | Content (μg/mL) | EE% | Size (nm)/PDI |
| 1 | 82.40 ± 2.72 | 91.93 ± 0.56 | 82.16 ± 0.97 | 111.2/0.17 |
| 3 | 73.44 ± 2.47 | 91.09 ± 0.59 | 81.98 ± 1.98 | 125.1/0.15 |
| 5 | 66.97 ± 1.48 | 90.81 ± 0.79 | 81.22 ± 2.65 | 115.7/0.19 |
| 7 | 59.38 ± 0.75 | 90.38 ± 1.73 | 80.74 ± 2.39 | 127.3/0.24 |
| 9 | 51.17 ± 0.61 | 89.57 ± 0.39 | 79.39 ± 0.55 | 129.8/0.39 |