Table 5.
3D quantitative surface texture parameters of HPMC/glipizide hydrophilic matrices (n = 10, standard deviations are in parenthesis).
| Parameter | K4M | K15M | K100M |
|---|---|---|---|
| Sa (μm) | 22.6 (2.3) | 14.6 (1.9) | 16.4 (3.3) |
| Sq (μm) | 26.5 (9.4) | 20.3 (3.5) | 23.7 (4.8) |
| Sz (μm) | 75.0 (7.2) | 60.0 (9.1) | 70.0 (10.9) |
| Sp (μm) | 33.7 (6.8) | 30.7 (4.9) | 36.3 (4.0) |
| Sv (μm) | 41.3 (9.0) | 29.4 (5.3) | 33.7 (8.4) |
| Sku (μm) | 5.3 (1.1) | 4.9 (0.9) | 5.1 (1.4) |
| Ssk (μm) | −0.6 (−0.1) | −0.4 (−0.2) | −0.7 (−0.2) |
| Sds (1/μm2) | 112.4 (11.4) | 98.3 (5.6) | 104.1 (9.7) |
| Sal (μm) | 136.4 (20.4) | 111.0 (11.0) | 121.4 (9.0) |
| Str | 0.9 (0.1) | 0.9 (0.1) | 0.8 (0.1) |
| Vm (μm3/μm2) | 0.4 (0.1) | 0.3 (0.09) | 0.4 (0.1) |
| Vv (μm3/μm2) | 6.9 (2.5) | 5.2 (2.89) | 6.4 (3.2) |
| Vvv (μm3/μm2) | 0.6 (0.1) | 0.4 (0.1) | 0.3 (0.1) |