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. 2019 Jul 11;9(7):140. doi: 10.3390/metabo9070140

Figure 1.

Figure 1

BRBs modulate the metabolic profile of oral cancer induced rats. (a) PCA of untargeted metabolomic profiles of urine samples from cancer-induced rats fed the control diet, 5% BRB diet, or 10% BRB diet as determined by LC-MS using the 292 features below the 0.05 p-value cutoff (ANOVA). (b) Loading scores for PC1 and PC2 for the top 292 features used in the PCA in (a). (c) Heat map of differentially expressed metabolites in 4NQO-exposed rats fed the control diet (4NQO), 5% BRB supplemented diet (4NQO + 5% BRB), or 10% BRB supplemented diet (4NQO + 10% BRB).