Figure 4.

Differential wiring in the methamphetamine high drinking (MAHDR) and methamphetamine low drinking (MALDR) lines. To facilitate comparison across regions, the connectivity and number of edges are computed only for the genes shared in common across the brain regions. The numbers of changed edges for the coexpression networks are shown in (a) for the ventral midbrain (VMB), (b) for the prefrontal cortex (PFC) and (c) for the nucleus accumbens (NAc). Genes significantly enriched in changed edges, relative to other genes in the same network, are depicted in red.