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. 2015 Mar 30;35(11):1292–1308. doi: 10.1002/jat.3132

Table 2.

Summary of liver tumors observed in male mice (NTP, 2013)

Liver Tumor Type 0 mg/kg 250 mg/kg 500 mg/kg
Hepatocellular adenoma or carcinoma 39/50 39/50 43/50 (P=0.2)a
Hepatoblastoma 2/50 11/50 (P=0.007) 8/50 (P=0.05)
Hepatocellular adenoma, hepatocellular carcinoma, or hepatoblastoma 39/50 42/50 (P=0.22) 43/50 (0.15)
a

P‐values for one‐sided Fisher's Exact Test.