Table 6.
Lifetime average daily dose (LADD) and cancer‐based margin of exposure (MOE) and margin of safety (MOS)
| Route of Exposure | Intake (mg/kg‐day) | ||
|---|---|---|---|
| Central Tendency | Upper‐Bound | Regulatory Default | |
| Total Dietary Intakea | 1.6E‐07 | 2.5E‐07 | 1.1E‐06 |
| Drinking Water | 5.0E‐09 | 1.6E‐08 | 5.4E‐08 |
| Soil/Dust | 5.4E‐08 | 3.7E‐07 | 2.7E‐06 |
| Total Dose | 2.2E‐07 | 6.4E‐07 | 3.9E‐06 |
| MOE b | 5.8E+08 | 2.0E+08 | 3.3E+07 |
| MOS c | 1.5E+03 | 5.0E+02 | 8.3E+01 |
a
Includes breast milk and food consumption as appropriate to the receptor.
b
Calculated using a POD of 126.6 mg/kg‐day.
c
Calculated using a RSD of 0.00032 mg/kg‐day (10−6 risk level).