. 2019 Jul 15;11(7):337. doi: 10.3390/pharmaceutics11070337

Table 1.

Characterization of poly(ionic liquid)s GPIL vs. LPIL (DDS type I).

No.	n_sc ^a	F_ChMAX ^b (mol %)	DP_sc ^c	DG ^d (%)	M_n,NMR (g/mol)	M_n,SEC ^e (g/mol)	Ð ^e	D_h ^f (nm)	DC (%)	Ref.
GPIL1.1	75	25	24	22	201,500	17,680	1.04	28	19	[44]
									6^g
GPIL1.2	75	67	12	22	127,000	19,500	1.04	56	32
GPIL1.3	75	71	28	22	314,500	19,000	1.10	51	36
GPIL1.4	105	74	39	53	724,100	30,400	1.06	22	38
GPIL1.5	185	74	43	74	1,498,500	828,700	1.28	40	39
LPIL1.1	-	78	187 *	-	49,200	6200	1.25	293	41	[39,40]
									49 ^g	[42]
LPIL1.2	-	45	119 *	-	23,100	8300	1.42	232	32	[39,40]
									51 ^g	[42]
GPIL2.1	165	19	26	53	579,000	nd	nd	24	20 ^g	[44]
									32 ^h
LPIL2.1	-	26	233 *	-	28,000	10,400	1.36	149	45 ^g	[42]
									11 ^h	[42]

GPIL: grafted poly(ionic liquid)s, where GPIL1: poly(MMA-co-(BIEM-graft-P(MMA-co-ChMASal)), GPIL2: poly(MMA-co-(BIEM-graft-P(MMA-co-ChMACl)); LPIL: linear poly(ionic liquid), where LPIL1: P(MMA-co-ChMASal), LPIL2: P(MMA-co-ChMACl); ^a number of side chains, ^b content of ionic units in polymer, ^c degree of polymerization of side chains, ^d degree of grafting related to n_sc per total DP of backbone, ^e determined in DMF, ^f determined in deionized water, ^g DLC of ERY for the weight ratio of polymer to encapsulated drug P:D = 1:1; ^h DLC of IMC for the weight ratio of P:D = 1:1; * DP of LPIL; nd – not determined.