Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 31;11:249–259. doi: 10.2147/BCTT.S208706

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Liang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Protocol for lung metastasis study.

Notes: (A) Protocol for examining the effect of APR-246 and 2aG4 antibody alone or in combination on lung metastasis of MDA-MB-435 TNBC cells in nude mice. (B) Animal weight during the treatment protocol shown in (A). Animals were weighed every 3–4 days throughout the experiment. Data represent mean±SEM (n=10–11/group). Control animals were treated with C44 antibody (ip). No significant weight differences were observed between control-treated animals and those administered APR-246 or 2aG4 alone or in combination using the one-way ANOVA on ranks (Dunn’s test).

Abbreviations: ANOVA, analysis of variance; ip, intraperitoneal; SEM, standard error of the mean; TNBC, triple-negative breast cancer.