Table 4.

Association of the HNF1A polymorphisms and the risk of CAD or IS in different genetic models

SNP/model	Genotype	OR (95% CI)CAD	p CAD	OR (95% CI)IS	p IS
Rs1169288
Codominant	AA	1		1
	CA	0.81 (0.62–1.05)	0.116	0.83 (0.62–1.10)	0.185
	CC	0.92 (0.62–1.37)	0.685	1.07 (0.70–1.62)	0.759
Dominant	AA	1		1
	AC + CC	0.84 (0.65–1.07)	0.158	0.88 (0.67–1.14)	0.333
Recessive	CC	1		1
	AA + AC	0.98 (0.68–1.42)	0.915	0.85 (0.58–1.26)	0.426
Rs2259820
Codominant	CC	1		1
	CT	0.89 (0.67–1.18)	0.410	0.91 (0.68–1.23)	0.556
	TT	0.64 (0.44–0.91)	0.015	0.72 (0.49–1.05)	0.090
Dominant	CC	1		1
	CT + TT	0.81 (0.63–1.06)	0.123	0.85 (0.64–1.13)	0.274
Recessive	TT	1		1
	CC + CT	1.47 (1.06–2.03)	0.020	1.32 (0.94–1.86)	0.109
Rs2464196
Codominant	GG	1		1
	GA	0.89 (0.68–1.18)	0.419	1.30 (0.91–1.87)	0.151
	AA	0.62 (0.43–0.89)	0.010	1.41 (0.96–2.07)	0.082
Dominant	GG	1		1
	GA + AA	0.81 (0.62–1.05)	0.116	0.86 (0.649–1.14)	0.296
Recessive	AA	1		1
	GG + GA	1.51 (1.09–2.08)	0.014	1.34 (0.96–1.89)	0.089
Rs2650000
Codominant	CC	1		1
	CA	0.84 (0.58–1.20)	0.334	0.90 (0.67–1.20)	0.465
	AA	0.88 (0.67–1.16)	0.370	0.80 (0.54–1.19)	0.273
Dominant	CC	1		1
	CA + AA	0.87 (0.67–1.12)	0.287	0.87 (0.66–1.15)	0.323
Recessive	AA	1		1
	CC + CA	1.12 (0.80–1.56)	0.513	0.85 (0.59–1.22)	0.382