Table 5.
Association of the HNF1A haplotypes and the risk of CAD or IS
| Haplotype | Control, n (%) | CAD, n (%) | OR (95% CI)CAD | p CAD | IS, n (%) | OR (95% CI)IS | p IS |
|---|---|---|---|---|---|---|---|
| A‐C‐G‐C | 599.67 (0.51) | 574.22 (0.51) | 1.10 (0.93–1.30) | 0.273 | 574.22 (0.51) | 1.11 (0.94–1.33) | 0.223 |
| C‐T‐A‐A | 357.70 (0.30) | 293.03 (0.26) | 0.85 (0.71–1.02) | 0.088 | 293.03 (0.26) | 0.94 (0.78–1.13) | 0.513 |
| A‐T‐A‐A | 73.15 (0.06) | 72.84 (0.06) | 1.09 (0.78–1.53) | 0.605 | 59.52 (0.06) | 0.94 (0.66–1.34) | 0.744 |
| A‐T‐A‐C | 86.49 (0.07) | 66.58 (0.06) | 0.83 (0.60–1.15) | 0.266 | 64.93 (0.06) | 0.86 (0.62–1.20) | 0.391 |
| A‐C‐G‐A | 20.69 (0.02) | 36.37 (0.03) | 1.95 (1.13–3.37) | 0.015 | 19.99 (0.02) | – | – |
The haplotypes consist of four alleles in the order: rs1169288, rs2259820, rs2464196 and rs2650000 SNPs.