Table 1.
Patient characteristics
| Patient characteristics | Total number =28 | |
|---|---|---|
| Age (median, range) | 68 (47–79) | |
| Sex | Female | 5 (18%) |
| Male | 23 (82%) | |
| ECOG PS | 0 | 11 (39.2%) |
| 1 | 17 (75.6%) | |
| Smoking history | Never smoker | 5 (18%) |
| Current or ex-smoker | 23 (82%) | |
| Histology | Adenocarcinoma | 19 (68%) |
| Squamous cell carcinoma | 9 (32%) | |
| Clinical stage | Stage IIIA | 1 (4%) |
| Stage IIIB | 5 (18%) | |
| Stage IV | 18 (64%) | |
| Postoperative recurrence | 4 (14%) | |
| EGFR mutation status | Deletion in exon19 | 5 (18%) |
| Exon 21 L858R | 3 (11%) | |
| Wild-type/Unknown | 18/2 (64%/7%) | |
| Number of prior regimens | 1 regimen | 24(86%) |
| 2 regimens | 4 (14%) | |
| Prior chemotherapy | CDDP + VNR | 1 (4%) |
| CDDP + PEM ± BEV | 10 (36%) | |
| CDDP + S-1 | 3 (11%) | |
| CBDCA + PEM ± BEV | 5 (18%) | |
| CBDCA + S-1 | 6 (21%) | |
| DTX | 3 (11%) | |