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. 2019 Aug 2;9(3):2045894019865169. doi: 10.1177/2045894019865169

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 2. — Effects of LIRI on antioxidant response and oxidative stress signal pathways. (a and b): Protein expression levels of Nrf2-ARE and SOD. Top panel and bottom panel are representative bands and averaged data: Nrf2/NQO1 and SOD were decreased in the cNTS of LIRI rats. *P < 0.05, LIRI rats versus control rats and sham control rats. n = 6–12 in each group. Insignificant difference was seen between control rats and sham control rats (P > 0.05). (c) Representative bands and averaged data showing that protein expression levels of NOX1, NOX2, and NOX3 were not altered significantly by LIRI, but NOX4 was amplified by LIRI. *P < 0.05, LIRI rats versus control rats and sham control rats. n = 6–10 in each group. Insignificant difference was seen between control rats and sham control rats (P > 0.05). SOD: superoxide dismutase.