Figure 6.

Formation of ROOOOR by the recombination of two lipid ROO^• (A), protein ROO^• (B), and DNA ROO^• (C). In (A–C), the recombination of two ROO^• results in the formation of unstable ROOH (reaction 1). ROOH can decompose either to ground carbonyl, ¹O₂ and ROH (reaction 2) or to ³R=O^*, molecular oxygen and ROH (reaction 3). The triplet-singlet energy transfer from ³R=O^* to molecular oxygen causes the formation of ¹O₂ (reactions 4). In (B), ROOH can decompose into two RO^• in the presence of reducing agents (reaction 5).