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. 2018 Mar 2;39(8):1557–1569. doi: 10.1177/0271678X18756218

Figure 5.

Figure 5.

(a) Effect of labelling plane location on CBF measurements. Negative label positions are located towards the tail of the animals, positive positions towards the nose; 0 mm is the position of the labelling plane shown in Figure 1, at which the labelling plane is entirely spanning straight and parallel vessels, each passing close to perpendicular through the labelling plane. ***p < 0.001, **p < 0.01, *p < 0.05; n = 9 across three strains. (b) Effect of label duration on CBF measurements: *p < 0.05; n = 9 across three strains. (c) Comparison between autoradiography (AR) and pCASL (1.4 s label duration) derived CBF values from ROIs covering (i) the whole brain, (ii) the cortex, or (iii) the striatum. (d) Example CBF maps obtained using (i) multiphase pCASL MRI and (ii) autoradiography in a Wistar rat.