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. Author manuscript; available in PMC: 2019 Aug 5.
Published in final edited form as: J Struct Biol. 2019 Mar 23;207(1):1–11. doi: 10.1016/j.jsb.2019.03.008

Table 1.

Quantitative evaluation. Study of inter-observer variability and method versus each observer independently (n = 12), reported as a mean ± standard deviation.

Semi-Automated vs. Observer 1 Semi-Automated vs. Observer 2 Inter-Observer
Sensitivity (SENS) 0.9 ± 0.07 0.92 ± 0.06 0.83±0.01
Specificity (SPEC) 0.99±0.02 0.98±0.01 0.99±0.01
Accuracy (ACC) 0.98±0.02 0.98±0.02 0.99±0.01
Dice Similarity Coefficient (DSC) 0.79 ± 0.07 0.79 ± 0.08 0.83 ± 0.05
Absolute Volume Difference (AVD) (%) 26.7 ± 23.2 32.7 ± 27 21.1 ± 16
Cohen’s Kappa (κ) 0.78 ± 0.08 0.76 ± 0.1 0.83 ± 0.05