Table 2.
Characteristics of HBsAg-positive mothers and their HBV-exposed children in four provinces, China 2016–2017
| Characteristics | N | % |
|---|---|---|
| Total | 4112 | 100.0 |
| Province | ||
| Guangdong | 1297 | 31.5 |
| Hebei | 920 | 22.4 |
| Shaanxi | 718 | 17.5 |
| Zhejiang | 1177 | 28.6 |
| Maternal age (years) | ||
| 18–24 | 280 | 6.8 |
| 25–34 | 2992 | 72.8 |
| 35–45 | 840 | 20.4 |
| Maternal educational level | ||
| Junior middle school and below | 1382 | 33.6 |
| High middle school and above | 2730 | 66.4 |
| Maternal residence rural/urban | ||
| Rural | 2818 | 68.5 |
| Urban | 1294 | 31.5 |
| Maternal Parity | ||
| 1 | 1732 | 42.1 |
| > 1 | 2380 | 57.9 |
| Maternal HBeAg status during this pregnancy | ||
| Positive | 1221 | 29.7 |
| Negative | 2740 | 66.6 |
| Unknown | 151 | 3.7 |
| Maternal HBV DNA during this pregnancy (IU/ml) | ||
| < 100 | 182 | 4.4 |
| 100–2 000 000 | 574 | 14.0 |
| > 2 000 000 | 291 | 7.1 |
| Unknown | 3065 | 74.5 |
| Maternal antiviral treatment during this pregnancy | ||
| Yes | 392 | 9.5 |
| No | 3720 | 90.5 |
| Level of delivery hospital | ||
| County level and below | 2594 | 63.1 |
| Prefectural and above | 1518 | 36.9 |
| Mode of delivery | ||
| Vaginal delivery | 2349 | 57.1 |
| Caesarean section | 1763 | 42.9 |
| Child age (months) | ||
| 7–12 | 1626 | 63.1 |
| 13–22 | 2486 | 36.9 |
| Child gender | ||
| Male | 2185 | 53.1 |
| Female | 1927 | 46.9 |
| Gestational age (weeks) | ||
| < 37 | 236 | 5.7 |
| 37–43 | 3876 | 94.3 |
| Child birth weight (g) | ||
| < 2500 (LBW) | 131 | 3.2 |
| 2500–5400 | 3981 | 96.8 |
| Interval between birth and HBvacc-BD (hours) | ||
| < 12 | 3579 | 87.0 |
| 12–24 | 466 | 11.3 |
| > 24 | 67 | 1.7 |
| Type of HBvacc-BD | ||
| 10 μg yeast vaccine | 3637 | 88.5 |
| 20 μg CHO vaccine | 285 | 6.9 |
| 10 μg CHO vaccine | 190 | 4.6 |
| Interval between birth and HBIG dose (hours) | ||
| < 12 | 3888 | 94.6 |
| 12–24 | 182 | 4.4 |
| > 24 | 22 | 0.5 |
| No | 20 | 0.5 |
| Received both HBvacc birth dose and HBIG within 12 h of birth | ||
| Yes | 3538 | 86.0 |
| No | 574 | 14.0 |
| Interval between third dose HBvacc and HBV serological test (months) | ||
| < 7 | 1666 | 40.5 |
| 7–18 | 2446 | 59.5 |
HBsAg hepatitis B surface antigen, HBV hepatitis B virus, HBeAg hepatitis B e antigen, HBvacc hepatitis B vaccine, HBvacc-BD hepatitis B vaccine birth dose, HBIG hepatitis B immunoglobulin, LBW low birth weight, CHO Chinese hamster ovary, IU international unit