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. 2019 Aug 2;9(3):2045894019859480. doi: 10.1177/2045894019859480

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 7. — Correlations of serum survivin with pulmonary hemodynamics and ROC curve for serum survivin. The serum survivin level was found to be correlated to the level of preoperative PVRi (a), postoperative mPAP (b), and ΔmPAP (c); negative correlation of serum survivin with mPAP (d), mPAP/MAP (e), and Qp/Qs (f). The correlations between the concentration of survivin and pulmonary hemodynamics were evaluated with Pearson's correlation coefficient, respectively. (g) ROC analysis for predicting the reversibility of PAH after shunt closure in patient with PAH secondary to CHD. (h) A positive correlation of serum survivin with BNP was observed. PVRi, pulmonary vascular resistance index; mPAP, mean pulmonary arterial pressure; ΔmPAP, the difference of mPAP between before surgery and after surgery; MAP, mean arterial pressure; Qp/Qs, pulmonary-to-systemic blood flow ratio; BNP, brain natriuretic peptide.