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Tumor response evaluation based on the WHO and RECIST criteria (stage 1: 15 patients; stage 2: 10 patients).
| Response evaluation | Stage 1 | Stage 2 | ||
|---|---|---|---|---|
| Cycle 2 (N = 15) | Cycle 4 (N = 8) | Cycle 2 (N = 10) | Cycle 4 (N = 5) | |
| WHO | ||||
| Partial response | 1∗ | 0 | 0 | 0 |
| Stable disease | 7 | 1 | 5 | 2 |
| Progressive disease | 5 | 5 | 4 | 3 |
| Others | 2 | 2 | 1 | 0 |
| RECIST | ||||
| Partial response | 0 | 0 | 0 | 0 |
| Stable disease | 9 | 2 | 5 | 4 |
| Progressive disease | 4 | 4 | 4 | 1 |
| Others | 2 | 2 | 1 | 0 |
∗Partial response was unconfirmed and thus not counted as clinical benefit.
