Table 1. . Considerations for informed consent for clinical genome and exome sequencing (CGES).

Personal and clinical contextual considerations
1. Decisions about CGES occur in the context of ongoing clinical decision-making
2. The consent process should be succinct and responsive to the patient’s personal situation and context
3. Information about basic genetics and technical descriptions of sequencing is often unnecessary
Results and implications
4. Focusing on the range of possible results including the limitations of current interpretations can promote reasonable expectations
5. Clinicians can facilitate decision-making and prepare patients for testing by discussing the potential clinical and emotional implications of results
6. Considering the implications of results for the patient’s family is an important part of the process*

CGES: Clinical genome and exome sequencing.