Growth inhibition, induction of apoptosis and inhibition of MDA-MB-231 and SKBR3 cell migration by buttressed analogs. Cells were treated for 24 h with different concentrations of the 3-Cl, 3,5-Br2 and 3-Cl-5-OCH3 buttressed analogs of DIM-C-pPhOH, and effects on cell growth inhibition (A), induction of Annexin V staining (B), and inhibition of cell migration in a Boyden chamber assay (C) were determined as outlined in the Materials and Methods. Results are expressed as means ± SE for at least 3 determinations for each treatment group and significant (p < 0.05) effects are indicated (*).