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. 2019 Jun 29;18(16):1908–1924. doi: 10.1080/15384101.2019.1632641

Figure 2.

Figure 2.

Overexpressed LINC00968 inhibits viability, migration and angiogenesis of BC cells. Lentivirus vector expressing LINC00968 was introduced into MDA-MB-231 cells to elevate the expression of LINC00968. (a), viability of MDA-MB-231 cells overexpressing LINC00968 detected by CCK-8 method. (b), migration of MDA-MB-231 cells overexpressing LINC00968 by Transwell assay (200 ×). (c), tube length and number of branches in HUVECs co-cultured with MDA-MB-231 cells overexpressing LINC00968 examined by tube formation assay (200 ×). (d), viability of MCF-7 cells overexpressing LINC00968 detected by CCK-8 method. (e), migration of MCF-7 cells overexpressing LINC00968 by Transwell assay (200 ×). (f), tube length and number of branches in HUVECs co-cultured with MCF-7 cells overexpressing LINC00968 examined by tube formation assay (200 ×). * p < 0.05, vs. the control group (cells without treatment) and the Lenti-NC group (cells transduced with Lenti-NC). the measurement data were expressed as mean ± standard deviation. Data among multiple groups were compared using one-way ANOVA, with Tukey post hoc test. Data at different time points were compared using repeated measurement ANOVA with Dunnett’s post hoc test. The experiment was repeated three times.