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. 2019 Jul 1;18(16):1849–1867. doi: 10.1080/15384101.2019.1629772

Figure 8.

Figure 8.

miR-139-5p inhibited the proliferation and viability of HCC cells. (a) Relative expression levels of SNHG6 and miR-139-5p in four transfection groups. (**P< 0.01, compared with NC group) (b) Cell viability of HepG2 cells was analyzed by MTT assay. OD value measurement was carried out in four transfection groups under 490 nm. (*P< 0.05, **P< 0.01, compared with NC group) (c) Colony numbers in four transfection groups were counted and compared. The inhibition of miR-139-5p showed a significant increase in the number of HCC cells. (*P< 0.05, compared with NC group) (d) Migration and invasion rate of HepG2 cells in different transfection groups, the migration cells and invasion cells per field suggested the migration and invasion rate of cells. (*P< 0.05, compared with NC group) (e) Cell cycle analysis of the cell cycle phase distribution. Representative cell cycle analysis (left panel). (*P< 0.05, compared with NC group). One-way ANOVA was used in Figure 8B. Student’s two-tailed t-test was used in the remaining figures. Every experiment was performed for 3 times at least.