20X H and E images from mice treated with high dose (>MTD (~392-707 mg.kg−1)) of Stöber SNPs500 for 10 days depicting organizing thrombi within pulmonary vessels (a-c), focal renal parenchymal damage, which appeared consistent with infarction (d-e), fibrosis and calcifications within cardiac wall, in keeping with older infarction (f), organizing brain infarcts with necro inflammatory infiltrate (g-h), marked retinal injury with calcification and gliosis (i). Black arrows point towards the histologic abnormalities.