Table 3.

Hematological profile of the mice treated with SNPs. The values are presented as red, blue and yellow colors which mean high, low and normal ranges, respectively. The gradient in high and low dose represented the percentage of the animals (e.g., dark red means 70-100% animals in those groups showed high level of the studied parameters). Abbreviations: Neutrophil (NEU), Lymphocyte (LYM), Monocyte (MONO), Eosinophil (EOS), Basophil (BAS), Red Blood Cell (RBC), Hemoglobin (HGB), Hematocrit (HCT), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), Red Blood Cell Distribution Width (RDW), Platelet (PLT) and Mean Platelet Volume (MPV) level.

Blood Cell Count Annalysis
Time	Treatment	Sex	Concentration (mg/kg)	NEU	LYM	MONO	EOS %	BAS %	RBC	HGB	HCT %	MCH	MCHC	RDW %	PLT	MPV
10 days	Stöber SNPs50	♀	>MTD
			MTD
			<MTD
			<<MTD
	Stöber SNPs500	♀	>>MTD
			>MTD
			MTD
		♂	>MTD
			>>MTD
	Mesoporous SNPs500	♀	MTD
			<MTD
			<<MTD
		♂	<<MTD
			<MTD
			MTD
	Control	♀	Control
		♂	Control
60 days	Stöber SNPs50	♀	MTD
		♂	MTD
	Stöber SNPs50	♀	MTD
		♂	MTD
	Mesoporous SNPs500	♀	MTD
		♂	MTD
	Control	♀	Control
		♂	Control
180 days	Stöber SNPs50	♀	MTD
		♂	MTD
	Stöber SNPs500	♀	MTD
		♂	MTD
	Mesoporous SNPs500	♀	MTD
		♂	MTD
	Control	♀	Control
		♂	Control
			Table Guidline:	high						low						Normal
				70-100%		50-70%		30-50%		70-100%		50-70%		30-50%