Table 1. Non-Myopathic Cardiac Complications Associated With Trastuzumab [6, 13-17].

Complications	Study	Symptoms	Further testing and results	Cardiomyopathy present
Asymptomatic new LBBB	Piotrowski et al [6]	No symptoms	No	No
New RBBB	Piotrowski et al [6]	No Symptoms	No	No
T-wave inversions in anterior leads	Olin et al [13]	Chest pain	Left heart catheterization revealed normal coronaries.	No
Sinus node dysfunction	Olin et al [13]	Syncope	No	No
Symptomatic new LBBB	Two studies (Tu et al [14] and Ribiero et al [15])	Chest pain and shortness of breath	Left heart catheterization revealed normal coronaries.	Yes
Ventricular tachycardia	Oliveira et al [16]	Sudden death	Autopsy showed LV hypertrophy, myocardial lymphocytic infiltrate, pulmonary congestion.	Yes
Non-sustained ventricular tachycardia	Ferguson et al [17]	palpitations and near-syncope	Holter revealed NSVT	No

LBBB: left bundle branch block; RBBB: right bundle branch block; LV: left ventricular; NSVT: non-sustained ventricular tachycardia.