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. 2019 Jul 20;42(7):557–567. doi: 10.14348/molcells.2019.0015

Fig. 6. Regulation of OC progression by TSPAN12 is highly associated with cyclin and CDK proteins.

Fig. 6

(A–D) Stable A2780, SKOV3 cells with TSPAN12 silencing were analyzed by western blot analysis of Cyclin A2, Cyclin E2, Cyclin D1, CDK2, and CDK4. (E-H) OVCAR3 and SKOV3 cells with TSPAN12 overexpression were analyzed by western blot analysis after being treated with or without CDK inhibitor, AT7519 (Inh, 100 nM) for 72 h. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. Data are presented as the mean ± standard deviation (SD) of three independent experiments.