TABLE B1.
Relative importance of the criteria elicited by clinician
Criteria | Value | Weights (w0) | |
---|---|---|---|
Efficacy | Schwab and England Activities of Daily Living Scale (SEADLS) CFB | 1–100 | 0.15 |
PDQ-39 Summary Index (PDSI) CFB | 0–100 | 0.10 | |
Ambulatory capacity (AC) CFB | 0–20 | 0.20 | |
Symbol Digit Modalities Test (SDMT) CFB | 0–110 | 0.10 | |
Modified Rankin Scale (MRS) decrease | 0 or 1 | 0.10 | |
Safety | Creatinine increase in blood CFB | 0 or 1 | 0.10 |
Weight increase | 0 or 1 | 0.05 | |
Oedema | 0 or 1 | 0.05 | |
Muscle spasms | 0 or 1 | 0.10 | |
Diarrhea | 0 or 1 | 0.05 |
CFB: change from baseline.