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. 2019 Aug 5;14(8):e0220685. doi: 10.1371/journal.pone.0220685

Table 8. Frequency, in absolute numbers, of the 10 most common drugs involved in potential C-interactions.

Rank Drug Interaction
frequency
1. Valproic acid 797
2. Lamotrigine 750
3. Carbamazepine 391
4. Azathioprine 336
5. Methotrexate 293
6. Mesalazine 270
7. Fluoxetine 213
8. Ipratropium 192
9. Sertraline 191
10. Topiramate 190
13. Phenobarbital 157
32. Cyclosporine 59

Only drugs with total prescribing of at least 50 were included in the table. The rank of the top 3 drugs in Table 9 are given at the bottom of Table 8 if they are not among the top ten in this table.