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. 2019 Aug 5;14(8):e0220685. doi: 10.1371/journal.pone.0220685

Table 10. Frequencies of D-interactions with various potential clinical effect in different age groups.

Age group (years) 0–2 3–5 6–11 12–17 Total
Potential adverse effect 13 15 20 119 167
Serotonin toxicity and/or anticholinergic side effects 0 0 3 84 87
Cardiac arrythmias 10 1 4 12 27
Bleeding 1 10 4 9 24
Sedation 0 1 6 2 9
Immunosuppressant toxicity 0 2 0 5 7
Other adverse effect (frequency <5) 2 1 3 7 13
Potential reduced effect 3 2 17 159 181
Reduced anti infective effect 0 0 6 67 73
Reduced analgesic effect 0 1 1 37 39
Reduced contraceptive effect 0 0 3 34 37
Reduced benzodiazepine effect 2 1 3 8 14
Reduced neuroleptic effect 0 0 2 8 10
Other reduced effect (frequency <5) 1 0 2 5 8
Total 16 17 37 278 348