Figure 5.

Cumulative release of VEGF from microspheres based on a 50:50 blend and a target VEGF loading of 1.0 wt %. The release was performed at 37 °C in PBS pH 7.4 supplemented with 0.025% Tween 20 and 0.02% NaN₃. Released VEGF was measured by ELISA (red) and SE-UPLC (blue), and plotted as cumulative release (filled blue and red circles, connected by a black line) and as a normalized cumulative release (blue and red circles). Normalized cumulative release data were fitted using the Korsmeyer–Peppas model (blue and red dotted lines). Parameters of this fit are listed in Table 2.