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. 2019 Jul 1;4(7):11481–11492. doi: 10.1021/acsomega.9b01272

Table 1. Formulation Characteristics of Three Batches of VEGF-Loaded Microspheres Prepared with a 50:50 Blend Ratio of Polymer A and B, per Batch and Average Values ± SD for Each Formulation Characteristic.

batch yield [%] average size [μm]; CV [%] feed loading [wt %] actual loading [wt %]a loading efficiency [%]
1 74 51; 15 1.00 0.72 72
2 73 52; 30 0.93 0.90 96
3 65 44; 17 1.13 0.76 67
average ± SD 71 ± 5 49 ± 4 1.02 ± 0.10 0.79 ± 0.09 78 ± 16
a

Loading of VEGF in microspheres was determined after destruction of loaded microspheres in DMSO and NaOH. VEGF content was quantified by BCA protein assay.