. 2019 Jul 10;4(7):11960–11972. doi: 10.1021/acsomega.9b01228

Table 1. Stability of (a) hSPR–Sepiapterin, (b) hSPR–Tranilast, (c) hSPR–NDGA, and (d) hSPR–SPRi3 Interactions throughout the 500 ns of the MD Simulations^a.

The green boxes indicate the presence of a hydrogen bond (bond strength >1 kcal/mol calculated in Molsoft). The grey boxes indicate no hydrogen bond of the hSPR residue with the drug.

Table 1. Stability of (a) hSPR–Sepiapterin, (b) hSPR–Tranilast, (c) hSPR–NDGA, and (d) hSPR–SPRi3 Interactions throughout the 500 ns of the MD Simulationsa.

Table 1. Stability of (a) hSPR–Sepiapterin, (b) hSPR–Tranilast, (c) hSPR–NDGA, and (d) hSPR–SPRi3 Interactions throughout the 500 ns of the MD Simulations^a.