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. 2019 Jul 9;4(7):11871–11879. doi: 10.1021/acsomega.9b01056

Table 2. In Vitro Synergistic Anti-candida Activity of BG8.

  MIC alone (μM)
MIC in combination (μM)
   
compound BG8 FLC BG8 FLC FICIa mode of interaction
C. albicans (ATCC 90028) 23.7 51.0 5.29 12.7 0.253 synergy
C. albicans D15.9a 23.7 3265 11.86 816 0.250 synergy
a

FICI = fractional inhibitory concentration index; synergy and antagonism were defined by FICI ≤ 0.5 and >4, respectively. Indifference was defined by 0.5 < FICI ≤ 4.