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. 2019 Jul 9;4(7):11871–11879. doi: 10.1021/acsomega.9b01056

Table 3. In Vitro Synergistic Anti-candida Activity of BG10.

  MIC alone (μM)
MIC in combination (μM)
   
compound BG10 FLC BG10 FLC FICIa mode of interaction
C. albicans (ATCC 90028) 21.8 51.0 2.73 6.36 0.127 synergy
C. albicans D15.9a 10.9 3265 1.36 816 0.250 synergy
a

FICI = fractional inhibitory concentration index; synergy and antagonism were defined by FICI ≤ 0.5 and >4, respectively. Indifference was defined by 0.5 < FICI ≤ 4.