Table 2.
Types of keywords used when searching for different areas of the potential drug-drug interaction information.
| Keyword types used | PDDIa topics assessed | |||||
| Existence of PPDIs, n (%) | Seriousness of PDDIs, n (%) | Clinical consequences of PDDIs, n (%) | Options to manage PDDIs, n (%) | Mechanism of a PDDI, n (%) | Health outcomes of a PDDI, n (%) | |
| Generic name | 20 (100) | 20 (100) | 20 (100) | 20 (100) | 19 (95) | 19 (95) |
| Drug class | 13 (65) | 11 (55) | 13 (65) | 12 (60) | 11 (55) | 10 (50) |
| Enzyme name or identifiers | 16 (80) | 10 (50) | 9 (45) | 10 (50) | 17 (85) | 6 (30) |
| Transporter names or identifiers | 15 (75) | 10 (50) | 10 (50) | 9 (45) | 19 (95) | 5 (25) |
| Keyword “drug interaction” | 15 (75) | 7 (35) | 8 (40) | 10 (50) | 10 (50) | 6 (30) |
| Ingredient names | 9 (45) | 8 (40) | 8 (40) | 8 (40) | 8 (40) | 8 (40) |
| Pharmacological pathway names or identifiers | 10 (50) | 6 (30) | 7 (35) | 5 (25) | 13 (65) | 4 (20) |
| Brand name | 6 (30) | 6 (30) | 6 (30) | 7 (35) | 5 (25) | 6 (30) |
| Drug product name | 5 (25) | 5 (25) | 6 (30) | 6 (30) | 4 (20) | 5 (25) |
| Drug identifiers | 5 (25) | 4 (20) | 5 (25) | 4 (20) | 2 (10) | 4 (20) |
| Specific author names | 2 (10) | 0 (0) | 2 (10) | 0 (0) | 1 (5) | 1 (5) |
aPPDI: potential drug-drug interaction.