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Activity of Compounds Identified from Initial Screen for Potentiation of Macrolide Antibiotics against AB5075 (MIC fold reductions in parentheses)
| Compound | MIC (μM) | Cone Tested (μM) | Erythromydn MIC (μg/mL) | Clarithromydn MIC (μg/mL) | Azithromycin MIC (μg/mL) |
|---|---|---|---|---|---|
| 32 | 32 | 64 | |||
| 1 | 100 | 30 | 4 (8) | 0.25 (128) | 8 (4) |
| 2 | 100 | 30 | 4 (8) | 0.25 (128) | 8 (4) |
