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. Author manuscript; available in PMC: 2020 Jul 12.
Published in final edited form as: ACS Infect Dis. 2019 Apr 26;5(7):1223–1230. doi: 10.1021/acsinfecdis.9b00067

Table 2.

Dose Dependent Resistance Suppression in AB5075 by Adjuvants 1 and 2

Cone Tested (μM) Erythromycin MIC (μg/mL) Clarithromycin MIC (μg/mL) Azithromycin MIC (μg/mL) Vancomycin MIC (μg/mL)
32 32 64 256
1 30 4 0.2S 8 1
20 4 0.5 16 8
15 8 0.5 16 64
10 8 2 16 256
5 16 16 32 256
2 30 4 0.2S 8 1
20 4 0.2S 16 4
15 8 0.5 16 32
10 8 2 32 128
5 16 8 64 256