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Combination of local and systemic immunity biomarkers in BCG responders and BCG nonresponders. (a) Total cell density of T-bet+ cells and (b) GATA-3+ cell normalized to the absolute lymphocyte counts. (c) The GTR/NLR immune score was obtained by normalizing the immune polarization in the tissue to the level of systemic inflammation (NLR). Differences were tested using Mann-Whitney U nonparametric test. GTR (GATA-3+/T-bet+ ratio). NLR (neutrophil-to-lymphocyte ratio).
