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. 2019 Apr 13;8(8):1602460. doi: 10.1080/2162402X.2019.1602460

Table 2.

Relationship between PD-L1 in tissue and other immune parameters.

  PD-L1 expression in Peritumoral immune cells
p-valuea
  ≤10% (n = 14)
  > 10% (n = 8)
   
  BCG
Responders (n = 8)
BCG
Nonresponders (n = 6)
p-
valueb
BCG
Responders (n = 4)
BCG
Nonresponders (n = 4)
p-valueb  
Age (years); median (IQR) 63 (60–77) 72 (61–78) 0.6 74 (64–85) 75 (68–84) 1 0.12
Absolute neutrophils count (x109/L); median (IQR) 4.5 (3.3–4.8) 4.6 (4–5.6) 0.6 4 (2.8–5.1) 5.4 (3–8.7) 0.6 0.9
Absolute lymphocyte count (x109/L); median (IQR) 2.1 (1.7–2.5) 2.1 (1.7–2.8) 1 2 (1.4–2.6) 1.2 (1.1–1.7) 0.1 0.04
NLR; median (IQR) 1.8 (1.6–2.7) 2 (1.8–2.6) 0.5 2.3 (1.3–3) 4.5 (2.7–5.2) 0.1 0.07
Total Peritumoral GATA-3+ cells; median (IQR) 630 (400–1012) 454(262–757) 0.2 1105 (395–1173) 662 (543–1420) 0.9 0.18
Total Peritumoral T-bet+ cells; median (IQR) 125(38–192) 235 (53–327) 0.2 134 (50–239) 265 (185–324) 0.1 0.6
GTR ratio; median (IQR) 6.2 (3.6–12.5) 2.5(1.5–6.8) 0.08 8 (5.1–8.6) 2.8 (2–6) 0.06 0.9

aComparison of low PD-L1 expression (≤10%) and high PD-L1 expression (> 10%); bComparison of BCG responders and BCG nonresponders.