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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Cancer Lett. 2019 Jul 6;461:1–9. doi: 10.1016/j.canlet.2019.07.002

Figure 5. Effect of combination mIR-125b transfection and paclitaxel chemotherapy on VEGF levels in the peritoneal cavity.

Figure 5.

Female C57BL/6 mice were injected with ID8 cells on day 1. On day 8th mice were injected intraperitoneally with PTX (2 mg/kg) and on day 10th mice were injected intraperitoneally with either HA-PEI-scrambled miR or HA-PEI-miR-125b at 1 mg/kg dose every alternate day for 3 days and peritoneal cavity was lavaged with 1X PBS on Day 16 and Day 24. (A) Representative peritoneal cavity images from these mice (B) Percent change in body weight determined over the duration of the study. (C) Accumulation of ascitic fluid volume on day 24. (D) Determination of the VEGF levels by ELISA in the peritoneal lavage from mice. N=4, Data is analyzed by One-way ANOVA.