Chen 2011.

Study characteristics
Patient sampling	Consecutive case series
Patient characteristics and setting	Location: Singapore National University Hospital, Singapore Prevalence = 54% N = 316 patients with mean age = 73 years, 87% Chinese, 53% female, with mean 6 years of education Memory clinic, consecutive patients over a 2 year period. Diagnosed using DSM‐IV criteria
Index tests	MoCA‐Singapore version
Target condition and reference standard(s)	AD Dementia, DSM IV, n = 172 (54%)
Flow and timing	None reported
Comparative
Notes	Conference abstract with limited information, extra information supplied by correspondence from author
Methodological quality
Item	Authors' judgement	Risk of bias	Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled?	Yes
Was a case‐control design avoided?	Yes
Did the study avoid inappropriate exclusions?	Unclear
		Unclear	Low
DOMAIN 2: Index Test All tests
Were the index test results interpreted without knowledge of the results of the reference standard?	Unclear
If a threshold was used, was it pre‐specified?	Unclear
Were sufficient data on MoCA application given for the test to be repeated in an independent study?	No
		Unclear	Unclear
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition?	Yes
Were the reference standard results interpreted without knowledge of the results of the index tests?	Unclear
Was sufficient information on the method of dementia assessment given for the assessment to be repeated in an independent study?	No
		Unclear	Low
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard?	Yes
Did all patients receive the same reference standard?	Unclear
Were all patients included in the analysis?	Unclear
		Unclear