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. 2015 Oct 29;2015(10):CD010775. doi: 10.1002/14651858.CD010775.pub2

Lee 2008.

Study characteristics
Patient sampling All participants were aged 65 and over and were recruited from among attenders at a community dementia care centre in Seoul where people without dementia can request memory testing. Most of the non‐dementia participants were recruited from this centre. AD patients were registered outpatients at Seoul National Hospital but it is not clear whether they had also attended the community dementia care centre. Thus sampling frame is unclear.
Patient characteristics and setting Location: Community dementia care centre and Seoul National University Boramae Hospital, Korea
Prevalence AD dementia = 22%
N = 196, 44 with AD, 37 with MCI, and 115 normal subjects (N)
Mean age: 70.4 in AD, 71.3 in MCI, 69.1 in N
% female: 52% in AD, 62% in MCI, 70% in N
Mean years education: 7.9 in AD, 8.3 in MCI, 8.0 in N
Index tests MoCA‐Korean
Target condition and reference standard(s) Dementia, CDR
Flow and timing No flow diagram available
Comparative  
Notes Extra information supplied by author
Methodological quality
Item Authors' judgement Risk of bias Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled? Unclear    
Was a case‐control design avoided? Unclear    
Did the study avoid inappropriate exclusions? Unclear    
    Unclear Unclear
DOMAIN 2: Index Test All tests
Were the index test results interpreted without knowledge of the results of the reference standard? Yes    
If a threshold was used, was it pre‐specified? No    
Were sufficient data on MoCA application given for the test to be repeated in an independent study? Yes    
    Low Low
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition? Yes    
Were the reference standard results interpreted without knowledge of the results of the index tests? Yes    
Was sufficient information on the method of dementia assessment given for the assessment to be repeated in an independent study? Unclear    
    Low Low
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard? Unclear    
Did all patients receive the same reference standard? Yes    
Were all patients included in the analysis? Unclear    
    Unclear