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. 2019 Jul 30;10:956. doi: 10.3389/fphys.2019.00956

FIGURE 1.

FIGURE 1

Ursolic Acid ameliorates liver injury and suppresses hepatic fibrogenesis in rats with CCl4-induced liver fibrosis. (A) Liver sections were stained with H&E and Picro-Sirius red, and representative images are shown. (B) Morphological changes in the liver sections quantified using the Metavir score. (C) The Sirius red stained area was quantified by Image-Pro Plus 6.0. (D) The protein levels of collagen I and α-SMA in liver tissues were analyzed by Western blot assays. (E) The level of hydroxyproline was measured by chemical oxidation. Original magnification: 100×. The data are presented as the means ± SD (n = 8 per group). *P < 0.05; ∗∗P < 0.01 versus the control group and ##P < 0.01 versus the CCl4 model group.