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. 2019 Jul 30;10:985. doi: 10.3389/fphys.2019.00985

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Copyright © 2019 Zhou, Xiao, Zhang, Zheng and Deng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Glucose metabolism of the male offspring at 24 weeks of age. (A) OGTT; (B) AUC; (C) serum insulin levels; (D) HOMA-IR. C, normal control diet; HF, high-fat diet; HFG, high-fat diet with genistein. OGTT, oral glucose tolerance test; AUC, area under the curve; HOMA-IR, the homeostasis model assessment of insulin resistance. Data are expressed as means ± S.E.M. (n = 7–8/group). Mean values were significantly different between C group and the HF group during OGTT: ^∗; Mean values were significantly different between HFG group and the HF group during OGTT: ^#. Mean values were significantly different between the groups: ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001, ^∗∗∗∗p < 0.0001.