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. 2019 Jul 30;10:856. doi: 10.3389/fphar.2019.00856

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Copyright © 2019 Rong, Wan, Fan, Liu, Sun, Huo, Zhang, Li, Xie, Wang and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of amentoflavone on cognitive deficits induced by PTZ kindling. (A) Statistical results showing the decrease in escape latency by amentoflavone (two-way ANOVA with repeated measures followed by Bonferroni or Dunnett’s T3 post hoc test). (B) Statistical results showing the decrease in swimming distance by rats in search of the hidden platforms due to amentoflavone treatment (Student’s t test). (C) Statistical results showing the increase in the number of rats crossing the target quadrant due to amentoflavone treatment (Student’s t test). (D) Statistical results showing the increase in the time spent in the target quadrant due to amentoflavone treatment (Chi-square test). Error bars represent mean ± s.d. **, *** represent p < 0. 01, p < 0.001, respectively. PTZ, pentylenetetrazole; AF, amentoflavone.