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. 2019 Jul 30;13:786. doi: 10.3389/fnins.2019.00786

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Copyright © 2019 Zhang, Ji, Yin, Wang, Zhou, Ni and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Different types of activation pattern and POC activation map. (A) Ascending-descending type. Bilateral POC activation was low at the low beginning, increased at the median, but decreased at the last high concentration. (B) Gradually ascending type. The POC activation showed a continuously increasing tendency as the concentration increased. (C) Gradually descending type. Bilateral POC activation was gradually decreased with the increase of odor concentration. (D) High plateau type. Bilateral POC activation remained at high level at all three different concentrations. (E) Low plateau type. Bilateral POC activation is little at three different concentrations. The A, C, D showed olfactory habituation and normal activation on the activation map, whereas the B, E implied an impaired olfactory function.