Table 2.
Hazard ratios (95% confidence intervals) for cardiovascular disease risk according to energy-adjusted dietary vitaminB6 intake levels stratified by sex.
| Vitamin B6 Intake (Quintile) | p for Trend | |||||
|---|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | Q5 | ||
| Men | ||||||
| n | 878 | 879 | 878 | 879 | 878 | |
| Case | 72 | 53 | 52 | 65 | 36 | |
| Person year | 7016 | 6002 | 5876 | 6305 | 7340 | |
| Range (median), mg/day | 1.01–1.83 (1.70) | 1.84–2.00 (1.93) | 2.01–2.16 (2.08) | 2.17–2.39 (2.26) | 2.40–6.22 (2.61) | |
| Model 1 | 1 | 0.88 (0.62, 1.25) | 0.88 (0.62, 1.26) | 1.02 (0.73, 1.43) | 0.48 (0.32, 0.71) | 0.001 |
| Model 2 | 1 | 1.04 (0.73, 1.49) | 1.11 (0.77, 1.59) | 1.42 (1.01, 2.00) | 0.68 (0.45, 1.02) | 0.3 |
| Model 3 | 1 | 0.96 (0.67, 1.39) | 0.98 (0.68, 1.43) | 1.27 (0.88, 1.82) | 0.56 (0.36, 0.86) | 0.048 |
| Model 4 | 1 | 0.90 (0.62, 1.32) | 0.89 (0.60, 1.33) | 1.10 (0.72, 1.67) | 0.44 (0.25, 0.78) | 0.02 |
| Women | ||||||
| n | 950 | 950 | 950 | 950 | 950 | |
| Case | 97 | 53 | 47 | 41 | 46 | |
| Person year | 8050 | 6890 | 6410 | 6514 | 7382 | |
| Range (median), mg/day | 0.88–1.73 (1.58) | 1.74–1.92 (1.84) | 1.93–2.08 (2.00) | 2.09–2.29 (2.17) | 2.30–7.51 (2.48) | |
| Model 1 | 1 | 0.65 (0.46, 0.90) | 0.62 (0.44, 0.88) | 0.53 (0.37, 0.77) | 0.52 (0.37, 0.74) | <0.001 |
| Model 2 | 1 | 0.70 (0.50, 0.98) | 0.74 (0.52, 1.05) | 0.74 (0.51, 1.08) | 0.75 (0.53, 1.07) | 0.1 |
| Model 3 | 1 | 0.77 (0.54, 1.09) | 0.84 (0.59, 1.22) | 0.86 (0.58, 1.27) | 0.76 (0.51, 1.13) | 0.2 |
| Model 4 | 1 | 0.78 (0.55, 1.12) | 0.88 (0.60, 1.30) | 0.93 (0.60, 1.43) | 0.87 (0.53, 1.44) | 0.6 |
Q, quintile. Model 1: unadjusted. Model 2: adjusted for age. Model 3: additionally adjusted for monthly household income, body mass index, educational levels, physical activity levels, residential area, smoking status, alcohol consumption, and hypertension and diabetes at baseline. Model 4: model 3 plus additionally adjusted total energy intake, three major nutrient factors identified in the principal component analysis and use of dietary supplement.