Figure 1.

Heatmap of differentially expressed genes (DEGs) that are significantly altered by cerulein treatment, or by pretreatment with docosahexaenoic acid (DHA) followed by cerulein treatment. AR42J cells were treated with a vehicle (designated as ‘none’) or DHA (50 μM) dissolved in vehicle (designated as ‘DHA’) for 6 h. For cerulein treatment, the cells were pretreated with a vehicle (designated as ‘cerulein’) or DHA (50 μM) dissolved in vehicle for 2 h and then stimulated with cerulein (10⁻⁸ M) (designated as ‘cerulein + DHA’) for 4 h. Vehicle is 0.5 M ethanol. Heatmap was drawn based on normalized read counts represented as FPKM (fragment per kilobase of transcript per million mapped reads).