Figure 2.

A schematic of the Ca²⁺ signaling network derived from Kyoto Encyclopedia of Genes and Genomes (KEGG). The filtered DEGs identified by the RNA-Seq analysis are colored in yellow boxes (ryanodine receptor (RYR), inositol triphosphate receptor (IP3R)). The molecular pathways associated with Ca²⁺ signaling are colored in light grey boxes (mitogen-activated protein kinase (MAPK), protein kinase A (PKA), Apoptosis, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), activator protein-1 (AP-1), phosphatidylinositol signaling pathways). The molecules in blue are second messengers in signaling transduction pathways.