Table 4.
Symptom scores.
| Control Group N = 25 | P-value | Intervention Group N = 80 | P-value | |
|---|---|---|---|---|
| IBS-SSS Total Score | ||||
| Baseline | 310 (247–351) | 306 (250–356) (2) | ||
| 2 weeks | 271 (238–325) (5) | 0.548 | 190 (118–282) (6) | <0.001 |
| 4 weeks | 300 (233–331) (2) | 0.248 | 156 (88–250) (8) | <0.001 |
| IBS-SSS Extra-Intestinal | ||||
| Baseline | 197 (106–257) | 184 (125–254) (3) | ||
| 2 weeks | 154 (121–241) (7) | 0.823 | 117 (77–215) (6) | <0.001 |
| 4 weeks | 169 (107–208) (3) | 0.231 | 98 (61–174) (6) | <0.001 |
| Psychological Well-Being | ||||
| Baseline | 47 (24–71) | 50 (24–69) (2) | ||
| 2 weeks | 49 (31–66) (5) | 0.658 | 41 (14–60) (6) | 0.002 |
| 4 weeks | 48 (32–60) (2) | 0.732 | 36 (13–53) (6) | <0.001 |
| Nausea | ||||
| Baseline | 29 (6–50) | 11 (1–34) (2) | ||
| 2 weeks | 20 (3–38) (5) | 0.820 | 4 (0–28) (6) | 0.011 |
| 4 weeks | 12 (2–56) (2) | 0.112 | 2 (0–24) (6) | 0.004 |
| Difficulty to Eat a Whole Portion | ||||
| Baseline | 9 (1–26) | 12 (1–30) (2) | ||
| 2 weeks | 8 (1–27) (5) | 0.941 | 4 (0–22) (6) | 0.003 |
| 4 weeks | 6 (1–20) (2) | 0.071 | 3 (0–17) (6) | <0.001 |
| Reflux | ||||
| Baseline | 17 (2–78) | 16 (3–54) (2) | ||
| 2 weeks | 14 (4–64) (5) | 0.806 | 5 (1–23) (6) | <0.001 |
| 4 weeks | 8 (1–50) (2) | 0.061 | 4 (0–21) (6) | <0.001 |
| Belching | ||||
| Baseline | 67 (20–84) | 71 (42–84) (3) | ||
| 2 weeks | 64 (36–81) (5) | 0.791 | 44 (15–60) (6) | <0.001 |
| 4 weeks | 59 (27–78) (2) | 0.246 | 26 (12–50) (6) | <0.001 |
| Headache | ||||
| Baseline | 31 (15–48) | 23 (7–67) (2) | ||
| 2 weeks | 30 (6–46) (5) | 0.378 | 24 (5–48) (6) | 0.009 |
| 4 weeks | 25 (8–35) (2) | 0.845 | 16 (4–36) (6) | 0.001 |
| Back Pain | ||||
| Baseline | 45 (19–66) | 37 (8–73) (2) | ||
| 2 weeks | 34 (7–54) (5) | 0.227 | 27 (6–53) (6) | 0.007 |
| 4 weeks | 32 (5–55) (2) | 0.249 | 20 (1–42) (6) | <0.001 |
| Leg Pain | ||||
| Baseline | 3 (0–16) | 4 (0–24) (2) | ||
| 2 weeks | 4 (1–12) (6) | 0.452 | 2 (0–16) (6) | 0.178 |
| 4 weeks | 4 (1–12) (2) | 0.924 | 2 (0–16) (6) | 0.006 |
| Muscle/Joint Pain | ||||
| Baseline | 21 (9–70) | 44 (12–70) (2) | ||
| 2 weeks | 25 (2–82) (3) | 0.290 | 30 (6–64) (6) | 0.022 |
| 4 weeks | 47 (8–74) (2) | 0.753 | 27 (6–50) (6) | <0.001 |
| Urinary Emergency | ||||
| Baseline | 20 (3–56) | 49 (18–73) (2) | ||
| 2 weeks | 21 (2–53) (6) | 0.401 | 26 (4–64) (6) | <0.001 |
| 4 weeks | 16 (1–43) (2) | 0.131 | 21 (1–47) (6) | <0.001 |
| Tiredness | ||||
| Baseline | 67 (39–91) | 65 (46–97) (2) | ||
| 2 weeks | 70 (46–84) (5) | 0.458 | 50 (26–73) (6) | <0.001 |
| 4 weeks | 65 (41–83) (2) | 0.794 | 48 (22–71) (6) | <0.001 |
IBS-SSS = Irritable bowel syndrome–symptom severity scale. Values are presented as median and interquartile rages (IQR). Wilcoxon’s test. P < 0.05 was considered statistically significant.